Dr. Sung-Cheol Kim
Department of Electrical and Computer Engineering
Seoul National University
A novel model that explains the dynamics of particles in deterministic lateral displacement arrays
Deterministic lateral displacement (DLD) is a technique for size-fractionation of particles in continuous flows that has shown great potential in biological and clinical applications. Several theoretical models were proposed to explain the trajectories of particles of different sizes concerning the geometry of the pillar array, but experimental evidence showed that an abundant class of other migration behavior exists. In this talk, a unified theoretical framework will be presented to infer the trajectory of particles in the whole array from the trajectories in the unit cell. This framework explains many of the unexpected particle trajectories reported in the literature and can be used to design arrays for the fractionation of particles at even the smallest scales reaching the subatomic realm. We also present experiments that validated our predictions even at the nanoscales and a practical application that separates nanoscale particles effectively.