close menu
Harry Asada

Contact Info

room 3-346

Massachusetts Institute of Technology

77 Massachusetts Avenue

Cambridge, Masachusetts 02139


  • 1973


  • 1975


  • 1979



Research Interests

  • Developing an assistance robot for passengers in railway stations.
  • Supernumerary Robotic Limbs
  • Nuclear Inspection Robots
  • Smart Actuators
  • Autonomous Mobile Robot Systems
  • Regulating Vascular Growth
  • Cytoskeleton Remodeling
  • Focal Adhesion Dynamics
  • Myogenesis

Honors + Awards

  • Engine and fuel interactions
  • Improving engine efficiency
  • Options for reducing transportation's greenhouse gas emissions


  • American Society of Mechanical Engineers
  • Institute of Electrical and Electronics Engineers

MIT Service

  • 2010-2014, Head, Area 3 - Control, Instrumentation, and Robotics, Mechanical Eng. Dept.
  • 2012-2013  Instrumentation and Robotics Faculty Search Committee
  • 2011           Strategic Planning Committee, Mechanical Eng. Dept.
  • 2010-2012  Bioengineering Faculty Search Committee
  • 2009-2009  Graduate Committee
  • 2007-2008  Robotics Faculty Search Committee


  • Introduction to Robotics (2.12/2.120)
  • Identification, Estimation, and Learning (2.160)
  • Systems and Controls (2.04A)


  • Farahat, W., and Asada, H., “Estimation of State Transition Probabilities in Asynchronous Vector Markov Processes”, ASME J. of Dynamic Systems, Measurement, and Control, [DOI: 10.1115/1.4006087], Vol. 134, November 2012.
  • Hahn, J.-O., Reisner, A., Jaffer, F.A., and Asada, H., “Subject-Specific Estimation of Central Aortic Blood Pressure Using an individualized Transfer Function: a Preliminary feasibility Study”, IEEE Transactions on Information Technology in Biomedicine, Issue 99, PMID: 22147332, Vol. 16, No. 2, pp. 212 – 220, March 2012.
  • Farahat, W., Wood, L., Zervantonakis, I., Schor, A., Ong, S., Neal, D., Kamm, R., and Asada, H., “Ensemble Analysis of Angiogenic Growth in Three-Dimensional Microfluidic Cell Cultures”, PLoS ONE, Vol. 7, Issue 5, e37333, doi:10.1371/journal.pone.0037333, April 2012.
  • Ge, R., Tan, E., Sharghi-Namini, Soheila, Asada, H., “Exosomes in Cancer Microenvironment and Beyond: Have We Overlooked These Extracellular Messengers?”, Cancer Microenvironment, Vol. 5, Issue 3, pp.323-332, DOI 10.1007/s12307-012-0110-2, May 2012.
  • Kim, Choong,  Chung, Seok,  Liu, Yuchun,  Kim, Min-Cheol,  Chan, Jerry K. Y., Asada, H., and Kamm, D., “In Vitro Angiogenesis Assay for the Study of Cell-Encapsulation Therapy”, in Lab on a Chip, Vol. 12, Issue 16, pp.2942-2950, DOI: 10.1039/C2LC40182G, May 2012.
  • Wood, L., Ge, R., Kamm, R., and Asada, H., "Nascent vessel elongation rate is inversely related to diameter in in vitro angiogenesis", Integrative Biology, Vol. 4, Issue 9, pp.1081-1089, DOI:10.1039/c2ib20054f, July 2012
  • Sakar, M.S., Neal, D., Boudou, T., Borochin, M., Lic, Y., Weiss, R. Kamm, R.D., Chen, C. and Asada, H., “Formation and optogenetic control of engineered 3D skeletal muscle bioactuators”, Lab on a Chip, 2012, Issue 23, pp. 4976-4985, DOI: 10.1039/C2LC40338B, October 2012, Front Cover Article, Lab-on-a-Chip top 10%.
  • Kim, M.-C.,  Kim, C.,  Wood, L., Neal, D., Kamm, R., and Asada, H., “Integrating Focal Adhesion Dynamics, Cytoskeleton Remodeling, and Actin Motor Activity for Predicting Cell Migration on 3D Curved Surfaces of Extracellular Matrix”, Integrative Biology, Vol. 4(11), pp. 1386-1397, DOI: 10.1039/C2IB20159C, September 2012
  • Kim, M.-C., Neal, D., Kamm, R., and Asada, H., “Dynamic Modeling of Cell Migration and Spreading Behaviors on Fibronectin Coated Planar Substrates and Micropatterned Geometries”, PLoS Computational Biology 9(2): e1002926, February, 2013.
  • Kim, M.-C., Lam, R.H.W., Thorsen, T., and Asada, H., “Mathematical Analysis of Oxygen Transfer through Polydimethylsiloxane Membrane between Double Layers of Cell Culture Channel and Gas Chamber in Microfluidic Oxygenator”, Microfluidics and Nanofluidics, Vol. 15, Issue 3, pp. 285-296,  February 2013.
  • Mazumdar, A., and Asada, H., “Pulse Width Modulation of Water Jet Propulsion Systems Using High Speed Coanda-Effect Valves”, ASME Journal of Dynamic Systems, Measurement, and Control, Vol. 135(5), pp. 051019(1)- (11), September 2013.
  • Torres, J., Asada, H. H., “High-Gain, High Transmissibility PZT Displacement Amplification Using a Rolling-Contact Buckling Mechanism and Preload Compensation Springs,” Transactions on Robotics, Vol. 30, Issue 4, pp. 781-791, August 2014.
  • Ong, L.-L.S., Dauwels, J., Ang, M., and Asada, H., “A Bayesian Filtering Approach to Incorporate 2D/3D Time-lapse Confocal Images for Tracking Angiogenic Sprouting Cells Interacting with the Gel Matrix”, Medical Image Analysis, Vol. 18, Issue 1, pp. 211-227, January 2014.
  • Chan V., Asada H. H., and Bashir, R., "Utilization and control of bioactuators across multiple length scales," Lab Chip, 2014 (Advanced Article), DOI: 10.1039/C3LC50989C, Front Cover Article, Lab on a Chip HOT article, Issue 4, pp. 653-670, November 2013.
  • Ang, X.M., Lee, M.H.C., Blocki, A., Chen, C., Ong, L.L.S., Asada, H.H., Sheppard, A., and Raghunath, M., “Macromolecular crowding amplifies adipogenesis of human bone marrow-derived MSCs by enhancing the pro-adipogenic microenvironment”, Tissue Engineering Part A, pp. 966-981, doi: 10.1089/ten.TEA.2013.0337, March 2014.
  • Herath, S., Yue, D., Hui, S., Kim, M.C., Wang, D., Wang, Q., Van Vliet K.J., Asada, H.H., Chen, P., “Quantification of Magnetically Induced Changes in ECM Local Apparent Stiffness”, Biophysical Journal, Vol.106, Issue 1, pp.332-341, January 1, 2014.
  • Mazumdar, A., Asada, H., “Control-Configured Design of Spheroidal, Appendage-Free, Underwater Vehicles,” IEEE Transactions on Robotics, Vol. 30, Issue 2, pp. 448-460, April 2014.
  • Neal, D., and Asada, H., “Bipolar Piezoelectric Buckling Actuators”, ASME/IEEE Transactions on Mechatronics, Vol. 19, No. 1, pp. 9-19, February 2014.
  • Sharghi-Namini, S., Tan, E., Ong, L.-L. S., Ge, R., and Asada, H.H., “Dll4-containing exosomes induce capillary sprout retraction in a 3D microenvironment”, Nature, Scientific Reports, Vol. 4, p.1-8, February 2014.
  • Neal, D., Sakar, M.S., Ong, L-L. S., Asada, H.H., “Formation of Elongated Fascicle-Inspired 3D Tissues Consisting of High-Density, Aligned Cells Using Sacrificial Outer Molding”, Lab on a Chip, pp. 448-460, March 2014, doi: 10.1039/C4LC00023D.
  • Herath, S., Du, Y., Wang, D., Liao, K., Wang, Q., Chen, P.C.Y., Asada, H., “Characterization of uniaxial stiffness of extracellular matrix embedded with magnetic beads via bio-conjugation and under the influence of an external magnetic field”, Journal of the Mechanical Behavior of Biomedical Materials, Vol. 30, pp. 253-265, February 2014.
  • Cvetkovic, C., Raman, R., Chan, V., Williams, B. J., Tolish, M., Bajaj, P., Bashir, R., Asada, H., "Three-dimensionally printed biological machines powered by skeletal muscle," Proceedings of the National Academy of Science, Vol. 111, pp. 10125-10130, July 2014.
  • Yan, J., Kang, Y., Xu, S., Ong, L.L.S., Zhuo, S., Bunte, R.M., Chen, N., Asada H.H., So, P.T.C., Wanless, I.R., Yu, H., "In vivo label-free quantification of liver microcirculation using dual-modality microscopy", Journal of Biomedical Optics, Vol.19(11), pp. 116006-1-116006-6, November 2014.


  • H. Asada and T. Kanade, "Robotics Manipulator", -- the patent of direct-drive robots-- US Patent 4,425,818, Issued on Jan. 17, 1984.
  • T. Kanade and H. Asada, "Non-Contact Visual Proximity Sensing Apparatus", US Patent 4,427,880, Issued on Jan. 24, 1984.
  • H. Asada and N. Goldfine, "Method for Grinding", US Patent 4,753,048, Issued on June 18, 1988.
  • C.C. Federspiel and H. Asada, "Controller for Air-Conditioner", US Patent 5,170,935, Issued on Dec. 15, 1992.
  • H. Asada, and A. Pil, "Method and Apparatus for the Recursive Design of Physical Structure, US Patent 5,684,343, Issued on November 04, 1997.
  • D. Braunstein, and H. Asada, "Apparatus for Real-Time Estimation of Printing", US Patent 5,988,856, Issued on November 23, 1999.
  • H. Asada, and M. Wada, "Reconfigurable Footprint Mechanism for Holonomic Omnidirectional Vehicles, US Patent 5,927,423, Issued July 27, 1999.
  • H. Asada and J. Spano, "Surface Wave Distributed Actuator Systems", US Patent 5,953,773, Issued September 21, 1999.
  • H. Asada, B.-H. Yang, and S.-W. Rhee, "Patient Monitoring Finger Ring Sensor", US Patent 5,964,701, Issued October 12, 1999.
  • H. Asada, S. Mascaro, and J. Spano, "Human Transport System with Dead Reckoning Facilitating Docking, US Patent 6,135,228, Issued October 2000.
  • H. Asada, K.-W. Chang, and S. Mascaro, "Finger Touch Sensors and Virtual Switch Panels", US Patent 6,236,037, Issued May 22, 2001.
  • H. Asada, C. Erin, and K.-Y. Siu, "Power Efficient Coding Protocol", US Patent 6,553,535, Issued April 22, 2003.
  • S.-W. Rhee, B.-H. Yang, and H. Asada, "A New Ring Sensor Design for Alleviaing the Influence of External Disturbance on the Finger Photoplethysmography", US Patent 6,402,690, Issued June 11, 2002.
  • H. Asada, B.-H. Yang, and Y. Zhang, "Cuff-less, Continuous Monitoring of Blood Pressure Using Hemodynamic Model", US Patent 6,413,223, Issued July 2, 2002.
  • H. Asada and S. Mascaro, "Fingernail Sensors for Measuring Finger Forces and Finger Posture", US Patent 6,388,247, Issued May 14, 2002.
  • H. Asada, R. C. Hutchinson, and P. Shaltis, S. Rhee, "Photoplethysmograph Signal-to-Noise Line Enhancement", US Patent 6,699,199, Issued March 2, 2004.
  • H. Asada and Philip Shaltis, "Vibratory Venous and Arterial Oximetry Sensor", US Patent 6,947,781, Issued September 20, 2005.
  • H. Asada, and Y. Zhang, "Multi-Channel Blind System Identification for Cardiovascular Monitoring", US Patent 7,169,111, Issued January 30, 2007.
  • H. Asada, K.J. Cho, and B. Selden, "Shape Memory Alloy Actuator System Using Segmented Binary Control", US Patent 7,188,473, Issued March 13, 2007.
  • X.-D. He and H. Asada, "Heating, Ventilation, and Air Conditioning (HVAC) System and Method using Feedback Linearization", US Patent 7,331,191 B2, Issued on February 19, 2008.
  • H. Asada, C-H. Liu, C. Erin, and K.-Y. Siu,"Source Coding for Interference Reduction", US Patent 7,376,105 B2, Issued on May 20, 2008.
  • D. McCombe, A. Reisner, H. Asada and P. Shaltis, "Wearable pulse wave velocity blood pressure sensor and methods of calibration thereof", US Patent 7,674,231, Issued on March 9, 2010
  • H. Asada, P. Shaltis, D. McCombe, and A. Reisner, "Wearable Blood Pressure Sensor and Method of Calibration", US Patent 7,641,614, Issued on January 5, 2010
  • H. Asada and M.C. Menon, "Rapid Cooling and Heating of Car Seats with Massaging Effect", US Patent 7,731,279, Issued on June 8, 2010.
  • X.-D. He, H. Asada, and T. Cheng, "Oil Circulation Observer for HVAC Systems", US Patent 7,895,846 B2, Issued on March 1, 2011.
  • B. Sarh and H. Asada, "Methods and Apparatus for an Instrumented Fastener", US Patent 7,937,817, Issued on May 10, 2011.
  • H. Asada, D. B. McCombie, A. T. Reisner, "Calibration of pulse transit time measurements to arterial blood pressure using external arterial pressure applied along the pulse transit path," US Patent No. 8,313,439, Issued on November 20, 2012.
  • H. Asada, M. Menon, and B. Sarh, "Electromagnetic Clamping Device", US Patent 8,490,955, Issued on July 23, 2013
  • H. Asada, B. Sarh, G. I. Karasic, "Robot Having Obstacle Avoidance Mechanism," US Patent No. 8,544,163, Issued on October 1, 2013.
  • H. Asada and D. M. Neal, "Phased Array Buckling Actuator," US Patent No. 8,593,035, Issued on November 26, 2013.