Fall | Graduate | 12 Units | Prereq: None
Bio(chemical) sensors play an outsized role in medical care, biological research, drug development, national security, and environmental monitoring, as exemplified by the current need for SARS-CoV-2 virus detection. Photonic biosensors use optical and plasmonic resonances to amplify biological signals associated with biological or chemical markers, and offer high-sensitivity detection, real-time readout, and scalable low-cost fabrication. The course will outline underlying physical and engineering principles that are used in photonic sensors to detect DNA molecules, proteins, and atmospheric/marine pollutants. These include fundamentals of light trapping and guiding, surface-polariton-mediated electromagnetic field enhancement, sensor surface functionalization, linear and non-linear light-matter interactions, refractometric sensing, fluorescence and Raman spectroscopy. The students will study and analyze commercial photonic biosensor systems, and will design novel sensor configurations in the context of SARS-CoV-2 virus detection and microplastic pollution monitoring. The students will also learn and practice the general principles of data sampling, statistical analysis and presentation of data acquired by biosensors.
Fall 2020 Update: Fully Remote Classes