Domitilla Del Vecchio received her Ph. D. in Control and Dynamical Systems from the California Institute of Technology, Pasadena, and the Laurea degree in Electrical Engineering (Automation) from the University of Rome at Tor Vergata in 2005 and 1999, respectively. From 2006 to 2010, she was an Assistant Professor in the Department of Electrical Engineering and Computer Science and in the Center for Computational Medicine and Bioinformatics at the University of Michigan, Ann Arbor. In 2010, she joined the Department of Mechanical Engineering at the Massachusetts Institute of Technology (MIT), where she is currently the Grover M. Hermann Professor in Health Sciences and Technology and a Professor of Mechanical and Biological Engineering. She was awarded a 2024 Vannevar Bush Faculty Fellowship, she is a Fellow of the International Federation of Automatic Control (2022), an IEEE Fellow (2021), a recipient of the Newton Award for Transformative Ideas during the COVID-19 Pandemic (2020), the 2016 Bose Research Award (MIT), the Donald P. Eckman Award from the American Automatic Control Council (2010), the NSF Career Award (2007), the American Control Conference Best Student Paper Award (2004), and the Bank of Italy Fellowship (2000). Her research focuses on developing modeling and biological engineering techniques to understand and control the behavior of genetic circuits in bacterial and mammalian cells. Her lab is particularly interested in applications to biosensing, biomanufacturing, and regenerative medicine.
The findings may redefine how cell identity is established and enable the creation of more sophisticated engineered tissues.
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Researchers find that cells’ chemical signaling includes a way to tell whether signals are being received or not.
UNIVERSITY OF ROME TOR VERGATA
Laurea in Electrical EngineeringCALIFORNIA INSTITUTE OF TECHNOLOGY
Ph.D. in Control and Dynamical SystemsDel Vecchio’s group focuses on analysis, design, and control of biomolecular networks in living cells. They build synthetic genetic systems to understand biology and use this understanding to control cellular processes. Target applications include biosensing, biomanufacturing, and regenerative medicine.
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